- M. Hashizume, A. Takashima, and M. Iwasaki*.
An mRNA-LNP-based Lassa virus vaccine induces protective immunity in mice.
bioRxiv. doi: 10.1101/2023.04.03.535313. 2023 - M. Hashizume, A. Takashima, C. Ono, T. Okamoto, and M. Iwasaki*.
Phenothiazines inhibit SARS-CoV-2 cell entry via a blockade of spike protein binding to neuropilin-1.
Antiviral Res. 209:105481. 2023 [PMID: 36481388] - K. Mizuma, A. Takashima, B. Cubitt, J. C. de la Torre, and M. Iwasaki*.
The Pan-ErbB tyrosine kinase inhibitor afatinib inhibits multiple steps of the mammarenavirus life cycle.
Virology. 576:83-95. 2022 [PMID: 36183499] - M. Hashizume, A. Takashima, and M. Iwasaki*.
A small stem-loop-forming region within the 3′-UTR of a non-polyadenylated LCMV mRNA promotes translation.
J Biol Chem. 298:101576. 2022 [PMID: 35026225] - S. Urata, J. Yasuda, and M. Iwasaki.
Loperamide Inhibits Replication of Severe Fever with Thrombocytopenia Syndrome Virus.
Viruses. 13:E869. 2021 [PMID: 34068464] - M. Hashizume, G. Gonzalez, C. Ono, A. Takashima, and M. Iwasaki*.
Population-Specific ACE2 Single-Nucleotide Polymorphisms Have Limited Impact on SARS-CoV-2 Infectivity In Vitro.
Viruses. 13:E67. 2021 [PMID: 33418950] - Y. Caì#, M. Iwasaki# (#, co-first authors), D. Motooka, D. X. Liu, S. Yú, K. Cooper, R. Hart, R. Adams, T. Burdette, E. N. Postnikova, J. Kurtz, M. St. Claire, C. Ye, J. H. Kuhn, L. Martínez-Sobrido, and J. C. de la Torre.
A Lassa Virus Live-Attenuated Vaccine Candidate Based on Rearrangement of the Intergenic Region.
mBio. 11:e00186-20. 2020 [PMID: 32209677] - Y. Caì, C. Ye, B. Cheng, A. Nogales, M. Iwasaki, S. Yú, K. Cooper, D. Z. Liu, R. Hart, R. Adams, T. Brady, E. N. Postnikova, J. Kurtz, M. St Claire, J. H. Kuhn, J. C. de la Torre, and L Martínez-Sobrido
A Lassa Fever Live-Attenuated Vaccine Based on Codon Deoptimization of the Viral Glycoprotein Gene.
mBio. 11:e00039-20. 2020 [PMID: 32098811] - Y. Caì, M. Iwasaki, B. F. Beitzel, S. Yú, E. N. Postnikova, B. Cubitt, L. E. DeWald, S. R. Radoshitzky, L. Bollinger, P. B. Jahrling, G. F. Palacios, J. C. de la Torre and J. H. Kuhn
Recombinant Lassa Virus Expressing Green Fluorescent Protein as a Tool for High-Throughput Drug Screens and Neutralizing Antibody Assays.
Viruses. 10:E655. 2018 [PMID: 30463334] - M. Iwasaki and J. C. de la Torre
A Highly Conserved Leucine In Mammarenavirus Matrix Z Protein Is Required For Z Interaction With The Virus L Polymerase And Z Stability In Cells Harboring An Active Viral Ribonucleoprotein.
J Virol. 92:e02256-17. 2018 [PMID: 29593035] - M. Iwasaki, P. Minder, Y. Caì, J. H. Kuhn, J. R. Yates III, B. E. Torbett, and J. C. de la Torre
Interactome Analysis of the Lymphocytic Choriomeningitis Virus Nucleoprotein in Infected Cells Reveals ATPase Na+/K+ Transporting Subunit Alpha 1 and Prohibitin as Host-Cell Factors Involved in the Life Cycle of Mammarenaviruses.
PLoS Pathog. 14:e1006892. 2018 [PMID: 29462184] - M. Iwasaki, S. M. Sharma, B. S. Marro, and J. C. de la Torre
Resistance Of Human Plasmacytoid Dendritic CAL-1 Cells To Infection With Lymphocytic Choriomeningitis Virus (LCMV) Is Caused By Restricted Virus Cell Entry, Which Is Overcome By Contact Of CAL-1 Cells With LCMV-Infected Cells.
Virology. 511:106-113. 2017 [PMID: 28843812] - M. Iwasaki, C. T. Ng, B. Cubitt, and J. C. de la Torre
Residues K465 and G467 Within The Cytoplasmic Domain of GP2 Critically Contribute To LCMV Persistence In Mice.
J Virol. 90:10102-10112. 2016 [PMID: 27581982] - M. Iwasaki, B. Cubitt, B. M. Sullivan, and J. C. de la Torre
The High Degree Of Sequence Plasticity Of The Arenavirus Non-Coding Intergenic Region (IGR) Enables The Use Of A Non-Viral Universal Synthetic IGR To Attenuate Arenaviruses.
J Virol. 90:3187-3197. 2016 [PMID: 26739049] - M. Iwasaki, N. Ngo, B. Cubitt, J. R. Teijaro, and J. C. de la Torre
General Molecular Strategy For Development Of Arenavirus Live-Attenuated Vaccines.
J Virol. 89:12166-12177. 2015 [PMID: 26401045] - M. Iwasaki, N. Ngo, B. Cubitt, and J. C. de la Torre
Efficient Interaction between Arenavirus Nucleoprotein (NP) and RNA-Dependent RNA Polymerase (L) Is Mediated by the Virus Nucleocapsid (NP-RNA) Template.
J Virol. 89:5734-5738. 2015 [PMID: 25762740] - M. Iwasaki, S. Urata, Y. Cho, N. Ngo, and J. C. de la Torre
Cell Entry of Lymphocytic Choriomeningitis Virus Is Restricted In Myotubes.
Virology. 458-459:22-32. 2014 [PMID: 24928036] - M. Iwasaki, N. Ngo, and J. C. de la Torre
Sodium hydrogen exchangers contribute to arenavirus cell entry.
J Virol. 88:643-654. 2014 [PMID: 24173224] - M. Ito#, M. Iwasaki# (#, co-first authors), M. Takeda, T. Nakamura, Y. Yanagi, and S. Ohno
Measles virus non-structural C protein modulates viral RNA polymerase activity by interacting with a host protein SHCBP1.
J Virol. 87:9633-9642. 2013 [PMID: 23804634] - Y. Nakatsu, X. Ma, F. Seki, T. Suzuki, M. Iwasaki, Y. Yanagi, K. Komase, and M. Takeda
Intracellular transport of the measles virus ribonucleoprotein complex is mediated by Rab11A-positive recycling endosomes and drives virus release from the apical membrane of polarized epithelial cells.
J Virol. 87:4683-4693. 2013 [PMID: 23408617] - M. Iwasaki* and Y. Yanagi
Expression of the Sendai (murine parainfluenza) virus C protein alleviates restriction of measles virus growth in mouse cells.
PNAS. 108:15384-15389. 2011 [PMID: 21896767] - Y. Nakatsu, M. Takeda, M. Iwasaki, and Y. Yanagi
A highly attenuated measles virus vaccine strain encodes a fully functional C protein.
J Virol. 83:11996-12001. 2009 [PMID: 19726523] - M. Iwasaki, M. Takeda, Y. Shirogane, Y. Nakatsu, T. Nakamura, and Y. Yanagi
The matrix protein of measles virus regulates viral RNA synthesis and assembly by interacting with the nucleocapsid protein.
J Virol. 83:10374-10383. 2009 [PMID: 19656884] - Y. Nakatsu, M. Takeda, S. Ohno, Y. Shirogane, M. Iwasaki, and Y. Yanagi
Measles virus circumvents the host interferon response by different actions of the C and V proteins.
J Virol. 82:8296-8306. 2008 [PMID: 18562542] - Y. Shirogane, M. Takeda, M. Iwasaki, N. Ishiguro, H. Takeuchi, Y. Nakatsu, M. Tahara, H. Kikuta, and Y. Yanagi
Efficient multiplication of human metapneumovirus in Vero cells expressing the transmembrane serine protease TMPRSS2.
J Virol. 82:8942-8946. 2008 [PMID: 18562527]
